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Itsuno-Corey Reduction - Corey-Bakshi-Shibata Readuction

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Itsuno-Corey Reduction - Corey-Bakshi-Shibata Readuction
This is the general form of the Itsuno-Corey reduction.

This is the general form of the Itsuno-Corey reduction, also known as the Corey-Bakshi-Shibata (CBS) reduction.

Todd Helmenstine
The Itsuno-Corey Reduction, also known as the Corey-Bakshi-Shibata Readuction (CBS reduction for short) is an enantioselective reduction of ketones in the presence of a chiral oxazaborolidine catalyst (CBS catalyst) and borane.

THF in this reaction is tetrahydrofuran.

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