Chan-Lam Coupling Reaction - Named Organic Reactions

The Chan-Lam coupling reaction forms aryl carbon-heteroatom bonds by combining arylboronic compounds, stannanes, or siloxanes with compounds containing either a N-H or O-H bond.

The reaction uses a copper as a catalyst which can be reoxidized by oxygen in the air at room temperature. Substrates can include amines, amides, anilines, carbamates, imides, sulfonamides and ureas.