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Why Does Hydrogen Peroxide Bubble on a Wound?

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Hydrogen peroxide is a weak acid with strong oxidizing properties.

Hydrogen peroxide is a weak acid with strong oxidizing properties. Oxygen bubbles are formed when you pour it over a wound, particularly one that is infected.

Ben Mills
Question: Why Does Hydrogen Peroxide Bubble on a Wound?
Have you ever wondered why hydrogen peroxide bubbles on a cut or wound, yet doesn't bubble on unbroken skin? Here's a look at the chemistry behind why hydrogen peroxide bubbles and what it means when it doesn't bubble.
Answer: Hydrogen peroxide bubbles when it comes into contact with an enzyme called catalase. Most cells in the body contain catalase, so when the tissue is damaged, the enzyme is released and becomes available to react with the peroxide. Catalase allows hydrogen peroxide (H2O2 to be broken down into water (H2O) and oxygen (O2). The bubbles you see when you pour oxygen on a cut are bubbles of oxygen gas. Blood, cells, and some bacteria (e.g., staphylococcus) contain catalase, but it is not found on the surface of your skin so pouring peroxide on unbroken skin will not cause bubbles to form. Also, because it is so reactive, hydrogen peroxide has a shelf life once it has been opened, so if you don't see bubbles form when peroxide is applied to an infected wound or bloody cut, there is a chance your peroxide is no longer active.

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