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Substituent Definition


This is the two-dimensional chemical structure of toluene, also known as methylbenzene or toluol.

This is the chemical structure of toluene. The methyl group, CH3 is a substituent attached to a benzene ring.

NEUROtiker, public domain

Definition: A substituent is an atom or functional group that replaces a hydrogen atom on a hydrocarbon.

In chemical structures, generic substituents are denoted by a capital R. If the substituent is a halide, a capital X.

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